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Shinichi Imamura Selected Research

PDGF receptor tyrosine kinase

4/2013Anti-angiogenic and anti-tumor effects of TAK-593, a potent and selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinase.
5/2012A novel pyrrolo[3, 2-d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet-derived growth factor receptor tyrosine kinase inhibitor, shows potent antitumor activity by suppression of tumor angiogenesis.

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Shinichi Imamura Research Topics

Disease

14Neoplasms (Cancer)
08/2020 - 10/2010
1Leukemia
01/2017
1Carcinogenesis
06/2013
1Adenocarcinoma of Lung
04/2013
1Prostatic Neoplasms (Prostate Cancer)
10/2010
1Stomach Neoplasms (Stomach Cancer)
12/2004

Drug/Important Bio-Agent (IBA)

4Phosphotransferases (Kinase)IBA
12/2013 - 05/2012
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013 - 12/2012
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2013 - 02/2011
2hypusineIBA
08/2020 - 01/2020
2Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
12/2013 - 06/2013
2PDGF receptor tyrosine kinaseIBA
04/2013 - 05/2012
2Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
05/2012 - 02/2011
1Eukaryotic Translation Initiation Factor 5AIBA
08/2020
1deoxyhypusine synthaseIBA
08/2020
1EnzymesIBA
08/2020
1Oncogene Proteins (Oncogene Protein)IBA
01/2020
1Messenger RNA (mRNA)IBA
01/2020
1ketodihydrosphingosineIBA
01/2018
1Serine C-PalmitoyltransferaseIBA
01/2018
1Lysine (L-Lysine)FDA Link
01/2017
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
06/2013
1LigandsIBA
06/2013
1Tyrosine (L-Tyrosine)FDA Link
06/2013
1N- (4- ((2- ((cyclopropylcarbonyl)amino)imidazo(1,2- a)pyridin- 6- yl)oxy)- 3- fluorophenyl)- 6- methyl- 2- oxo- 1- phenyl- 1,2- dihydropyridine- 3- carboxamideIBA
06/2013
1Proto-Oncogene Proteins c-metIBA
06/2013
1TAK 593IBA
04/2013
1pyrimidineIBA
05/2012
1Oxygen (Dioxygen)IBA
02/2011
1Protein Kinases (Protein Kinase)IBA
02/2011
1Dendrimers (Dendrons)IBA
01/2011
1SaltsIBA
10/2010
1titanium silicide (TS-1)IBA
12/2004

Therapy/Procedure

6Oral Administration
01/2018 - 10/2010
3Therapeutics
01/2018 - 12/2004